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Anti-RNF220 Antibody Picoband®

Boster Bio Anti-RNF220 Antibody Picoband® catalog # A11818-1. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Enables beta-catenin binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within positive regulation of DNA-binding transcription factor activity and protein monoubiquitination. Located in nuclear lamina. Part of protein-containing complex. Implicated in hypomyelinating leukodystrophy 23.

Synonyms

RNF220; C1orf164; E3 ubiquitin-protein ligase RNF220; EC 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220

Gene Name

RNF220

Gene ID

55182

UniProt

Q5VTB9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human RNF220 recombinant protein (Position: M1-L566) . Human RNF220 shares 97.9% amino acid (aa) sequence identity with mouse RNF220.

Clonality

Polyclonal

Applications

WB, IHC, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/12/2014. 2. Kong, Q., Zeng, W., Wu, J., Hu, W., Li, C., Mao, B. RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination. Biochem. Biophys. Res. Commun. 393: 708-713, 2010. 3. Leuzzi, V., Rinna, A., Gallucci, M., Di Capua, M., Dionisi-Vici, C., Longo, D., Bertini, E. Ataxia, deafness, leukodystrophy: inherited disorder of the white matter in three related patients. Neurology 54: 2325-2328, 2000.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

63 kDa

Observed Molecular Weight

63 kDa

Applications Notes

6

Gene Name Synonym

Ring finger protein 220

Protein Name

E3 ubiquitin-protein ligase RNF220

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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