Anti-RNF220 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables beta-catenin binding activity. Involved in positive regulation of canonical Wnt signaling pathway. Acts upstream of or within positive regulation of DNA-binding transcription factor activity and protein monoubiquitination. Located in nuclear lamina. Part of protein-containing complex. Implicated in hypomyelinating leukodystrophy 23.
Synonyms
RNF220; C1orf164; E3 ubiquitin-protein ligase RNF220; EC 2.3.2.27; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220
Gene Name
RNF220
Gene ID
55182
UniProt
Q5VTB9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human RNF220 recombinant protein (Position: M1-L566) . Human RNF220 shares 97.9% amino acid (aa) sequence identity with mouse RNF220.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/12/2014. 2. Kong, Q., Zeng, W., Wu, J., Hu, W., Li, C., Mao, B. RNF220, an E3 ubiquitin ligase that targets Sin3B for ubiquitination. Biochem. Biophys. Res. Commun. 393: 708-713, 2010. 3. Leuzzi, V., Rinna, A., Gallucci, M., Di Capua, M., Dionisi-Vici, C., Longo, D., Bertini, E. Ataxia, deafness, leukodystrophy: inherited disorder of the white matter in three related patients. Neurology 54: 2325-2328, 2000.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
63 kDa
Gene Name Synonym
Ring finger protein 220
Protein Name
E3 ubiquitin-protein ligase RNF220
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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