Anti-SV2C Antibody Picoband® APC Conjugated
Product Specifications
Background
Predicted to enable transmembrane transporter activity. Predicted to be involved in several processes, including chemical synaptic transmission; neurotransmitter transport; and regulation of synaptic vesicle exocytosis. Predicted to be located in plasma membrane and synaptic vesicle. Predicted to be active in dopaminergic synapse and synaptic vesicle membrane.
Synonyms
SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C
Gene Name
SV2C
Gene ID
22987
UniProt
Q496J9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SV2C recombinant protein (Position: M1-A579) . Human SV2C shares 96.7% and 96.5% amino acid (aa) sequence identity with mouse and rat SV2C, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Benoit, R. M., Frey, D., Hilbert, M., Kevenaar, J. T., Wieser, M. M., Stirnimann, C. U., McMillan, D., Ceska, T., Lebon, F., Jaussi, R., Steinmetz, M. O., Schertler, G. F. X., Hoogenraad, C. C., Capitani, G., Kammerer, R. A. Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A. Nature 505: 108-111, 2014. 2. Dong, M., Yeh, F., Tepp, W. H., Dean, C., Johnson, E. A., Janz, R., Chapman, E. R. SV2 is the protein receptor for botulinum neurotoxin A. Science 312: 592-596, 2006. 3. Iezzi, M., Theander, S., Janz, R., Loze, C., Wollheim, C. B. SV2A and SV2C are not vesicular Ca (2+) transporters but control glucose-evoked granule recruitment. J. Cell Sci. 118: 5647-5660, 2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A10958-1-APC
Calculated Molecular Weight
82 kDa
Applications Notes
6
Gene Name Synonym
Synaptic vesicle glycoprotein 2C
Protein Name
Synaptic vesicle glycoprotein 2C
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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