Anti-PXDN Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.
Synonyms
PXDN; KIAA0230; MG50; PRG2; VPO; VPO1; Peroxidasin homolog; EC 1.11.1.7; Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 protein
Gene Name
PXDN
Gene ID
7837
UniProt
Q92626
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PXDN recombinant protein (Position: R900-D1054) . Human PXDN shares 94.8% amino acid (aa) sequence identity with mouse PXDN.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Cheng, G., Salerno, J. C., Cao, Z., Pagano, P. J., Lambeth, J. D. Identification and characterization of VPO1, a new animal heme-containing peroxidase. Free Radic. Biol. Med. 45: 1682-1694, 2008. 2. Choi, A., Lao, R., Ling-Fung Tang, P., Wan, E., Mayer, W., Bardakjian, T., Shaw, G. M., Kwok, P., Schneider, A., Slavotinek, A. Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis. Europ. J. Hum. Genet. 23: 337-341, 2015. 3. Horikoshi, N., Cong, J., Kley, N., Shenk, T. Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene. Biochem. Biophys. Res. Commun. 261: 864-869, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
165 kDa
Gene Name Synonym
Peroxidasin
Protein Name
Peroxidasin homolog
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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