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Anti-PXDN Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.

Synonyms

PXDN; KIAA0230; MG50; PRG2; VPO; VPO1; Peroxidasin homolog; EC 1.11.1.7; Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 protein

Gene Name

PXDN

Gene ID

7837

UniProt

Q92626

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PXDN recombinant protein (Position: R900-D1054) . Human PXDN shares 94.8% amino acid (aa) sequence identity with mouse PXDN.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Cheng, G., Salerno, J. C., Cao, Z., Pagano, P. J., Lambeth, J. D. Identification and characterization of VPO1, a new animal heme-containing peroxidase. Free Radic. Biol. Med. 45: 1682-1694, 2008. 2. Choi, A., Lao, R., Ling-Fung Tang, P., Wan, E., Mayer, W., Bardakjian, T., Shaw, G. M., Kwok, P., Schneider, A., Slavotinek, A. Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis. Europ. J. Hum. Genet. 23: 337-341, 2015. 3. Horikoshi, N., Cong, J., Kley, N., Shenk, T. Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene. Biochem. Biophys. Res. Commun. 261: 864-869, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

165 kDa

Gene Name Synonym

Peroxidasin

Protein Name

Peroxidasin homolog

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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