Anti-RAI3/GPRC5A Antibody Picoband®

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.

GPRC5A; GPCR5A; RAI3; RAIG1; Retinoic acid-induced protein 3; G-protein coupled receptor family C group 5 member A; Phorbol ester induced gene 1; PEIG-1; Retinoic acid-induced gene 1 protein; RAIG-1

A synthetic peptide corresponding to a sequence in the middle region of human RAI3/GPRC5A. Human RAI3/GPRC5A shares 95.2% amino acid (aa) sequence identity with mouse RAI3/GPRC5A.

1. Bjarnadottir, T. K., Fredriksson, R., Schioth, H. B. The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste (1) and other related G protein-coupled receptors. Gene 362: 70-84, 2005. 2. Cafferata, E. G., Gonzalez-Guerrico, A. M., Pivetta, O. H., Santa-Coloma, T. A. Identification by differential display of a mRNA specifically induced by 12-o-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells. Cell. Molec. Biol. (Noisy-le-grand) 42: 797-804, 1996. 3. Cheng, Y., Lotan, R. Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. J. Biol. Chem. 273: 35008-35015, 1998.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.