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Anti-RAI3/GPRC5A Antibody Picoband® HRP Conjugated

Product Specifications

Background

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.

Synonyms

GPRC5A; GPCR5A; RAI3; RAIG1; Retinoic acid-induced protein 3; G-protein coupled receptor family C group 5 member A; Phorbol ester induced gene 1; PEIG-1; Retinoic acid-induced gene 1 protein; RAIG-1

Gene Name

GPRC5A

Gene ID

9052

UniProt

Q8NFJ5

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human RAI3/GPRC5A. Human RAI3/GPRC5A shares 95.2% amino acid (aa) sequence identity with mouse RAI3/GPRC5A.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Bjarnadottir, T. K., Fredriksson, R., Schioth, H. B. The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste (1) and other related G protein-coupled receptors. Gene 362: 70-84, 2005. 2. Cafferata, E. G., Gonzalez-Guerrico, A. M., Pivetta, O. H., Santa-Coloma, T. A. Identification by differential display of a mRNA specifically induced by 12-o-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells. Cell. Molec. Biol. (Noisy-le-grand) 42: 797-804, 1996. 3. Cheng, Y., Lotan, R. Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. J. Biol. Chem. 273: 35008-35015, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

40 kDa

Gene Name Synonym

G protein-coupled receptor class C group 5 member A

Protein Name

Retinoic acid-induced protein 3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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