Anti-GPR35 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables C-X-C chemokine receptor activity. Involved in chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Located in plasma membrane.
Synonyms
GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor
Gene Name
GPR35
Gene ID
2859
UniProt
Q9HC97
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human GPR35. Human GPR35 shares 95% amino acid (aa) sequence identity with mouse GPR35.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Horikawa, Y., Oda, N., Cox, N. J., Li, X., Orho-Melander, M., Hara, M., Hinokio, Y., Lindner, T. H., Mashima, H., Schwarz, P. E. H., del Bosque-Plata, L., Horikawa, Y., and 14 others. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genet. 26: 163-175, 2000. Note: Erratum: Nature Genet. 26: 502 only, 2000. 2. Maravillas-Montero, J. L., Burkhardt, A. M., Hevezi, P. A., Carnevale, C. D., Smit, M. J., Zlotnik, A. Cutting edge: GPR35/CXCR8 is the receptor of the mucosal chemokine CXCL17. J. Immun. 194: 29-33, 2015. 3. O'Dowd, B. F., Nguyen, T., Marchese, A., Cheng, R., Lynch, K. R., Heng, H. H. Q., Kolakowski, L. F., Jr., George, S. R. Discovery of three novel G-protein-coupled receptor genes. Genomics 47: 310-313, 1998.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
34 kDa
Gene Name Synonym
G protein-coupled receptor 35
Protein Name
G-protein coupled receptor 35
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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