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Anti-PTCD3 Antibody Picoband® Cy3 Conjugated

Product Specifications

Background

Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol; mitochondrial matrix; and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.

Synonyms

PTCD3; MRPS39; TRG15; Pentatricopeptide repeat domain-containing protein 3, mitochondrial; 28S ribosomal protein S39, mitochondrial; MRP-S39; Mitochondrial small ribosomal subunit protein mS39; Transformation-related gene 15 protein; TRG-15

Gene Name

PTCD3

Gene ID

55037

UniProt

Q96EY7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PTCD3 recombinant protein (Position: D66-R648) . Human PTCD3 shares 76.4% amino acid (aa) sequence identity with mouse PTCD3.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10795-1-Cy3

Calculated Molecular Weight

79 kDa

Applications Notes

6

Gene Name Synonym

Pentatricopeptide repeat domain 3

Protein Name

Small ribosomal subunit protein mS39

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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