Anti-PTCD3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol; mitochondrial matrix; and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.
Synonyms
PTCD3; MRPS39; TRG15; Pentatricopeptide repeat domain-containing protein 3, mitochondrial; 28S ribosomal protein S39, mitochondrial; MRP-S39; Mitochondrial small ribosomal subunit protein mS39; Transformation-related gene 15 protein; TRG-15
Gene Name
PTCD3
Gene ID
55037
UniProt
Q96EY7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PTCD3 recombinant protein (Position: D66-R648) . Human PTCD3 shares 76.4% amino acid (aa) sequence identity with mouse PTCD3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
79 kDa
Gene Name Synonym
Pentatricopeptide repeat domain 3
Protein Name
Small ribosomal subunit protein mS39
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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