Anti-PTCD3 Antibody Picoband® Biotin Conjugated

Enables rRNA binding activity and ribosomal small subunit binding activity. Involved in mitochondrial translation. Located in several cellular components, including cytosol; mitochondrial matrix; and nucleoplasm. Implicated in combined oxidative phosphorylation deficiency 51.

PTCD3; MRPS39; TRG15; Pentatricopeptide repeat domain-containing protein 3, mitochondrial; 28S ribosomal protein S39, mitochondrial; MRP-S39; Mitochondrial small ribosomal subunit protein mS39; Transformation-related gene 15 protein; TRG-15

1. Borna, N. N., Kishita, Y., Kohda, M., Lim, S. C., Shimura, M., Wu, Y., Mogushi, K., Yatsuka, Y., Harashima, H., Hisatomi, Y., Fushimi, T., Ichimoto, K., Murayama, K., Ohtake, A., Okazaki, Y. Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. Neurogenetics 20: 9-25, 2019. 2. Davies, S. M. K., Rackham, O., Shearwood, A.-M. J., Hamilton, K. L., Narsai, R., Whelan, J., Filipovska, A. Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation. FEBS Lett. 583: 1853-1858, 2009. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 11/6/2012.