Anti-PSMA6 Antibody Picoband® Biotin Conjugated

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

PSMA6; PROS27; Proteasome subunit alpha type-6; EC 3.4.25.1; 27 kDa prosomal protein; PROS-27; p27K; Macropain iota chain; Multicatalytic endopeptidase complex iota chain; Proteasome iota chain

E.coli-derived human PSMA6 recombinant protein (Position: M1-D246) . Human PSMA6 shares 99.6% and 100% amino acid (aa) sequence identity with mouse and rat PSMA6, respectively.

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