Anti-PFDN2 Antibody Picoband® Fluoro647 Conjugated

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.

E.coli-derived human PFDN2 recombinant protein (Position: K18-Q98) . Human PFDN2 shares 98.8% amino acid (aa) sequence identity with both mouse and rat PFDN2.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 6/29/2010. 2. Hutchins, J. R. A., Toyoda, Y., Hegemann, B., Poser, I., Heriche, J.-K., Sykora, M. M., Augsburg, M., Hudecz, O., Buschhorn, B. A., Bulkescher, J., Conrad, C., Comartin, D., and 18 others. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 328: 593-599, 2010. 3. Vainberg, I. E., Lewis, S. A., Rommelaere, H., Ampe, C., Vandekerckhove, J., Klein, H. L., Cowan, N. J. Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell 93: 863-873, 1998.