Anti-SGCZ Antibody Picoband® HRP Conjugated
Product Specifications
Background
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
Synonyms
SGCZ; Zeta-sarcoglycan; Zeta-SG; ZSG1
Gene Name
SGCZ
Gene ID
137868
UniProt
Q96LD1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SGCZ recombinant protein (Position: M1-L245) . Human SGCZ shares 97.1% amino acid (aa) sequence identity with mouse SGCZ.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Wheeler, M. T., Zarnegar, S., McNally, E. M. Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Hum. Molec. Genet. 11: 2147-2154, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
33 kDa
Gene Name Synonym
Sarcoglycan zeta
Protein Name
Zeta-sarcoglycan
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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