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Anti-SEZ6L2 Antibody Picoband® HRP Conjugated

Product Specifications

Background

This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants.

Synonyms

SEZ6L2; PSK; UNQ1903/PRO4349; Seizure 6-like protein 2

Gene Name

SEZ6L2

Gene ID

26470

UniProt

Q6UXD5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SEZ6L2 recombinant protein (Position: E33-I910) . Human SEZ6L2 shares 96.4% amino acid (aa) sequence identity with mouse SEZ6L2.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 11/30/2015. 2. Miyazaki, T., Hashimoto, K., Uda, A., Sakagami, H., Nakamura, Y., Saito, S., Nishi, M., Kume, H., Tohgo, A., Kaneko, I., Kondo, H., Fukunaga, K., Kano, M., Watanabe, M., Takeshima, H. Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family. FEBS Lett. 580: 4057-4064, 2006.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

98 kDa

Gene Name Synonym

Seizure related 6 homolog like 2

Protein Name

Seizure 6-like protein 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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