Anti-PIP5K1B Antibody Picoband® APC Conjugated

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in uropod.

PIP5K1B; STM7; Phosphatidylinositol 4-phosphate 5-kinase type-1 beta; PIP5K1-beta; PtdIns (4P-5-kinase 1 beta; EC 2.7.1.68; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PIP5KIbeta; Protein STM-7; Type I phosphatidylinositol 4-phosphate 5-kinase beta

E.coli-derived human PIP5K1B recombinant protein (Position: R394-L540) . Human PIP5K1B shares 96.6% and 95.2% amino acid (aa) sequence identity with mouse and rat PIP5K1B, respectively.

1. Campuzano, V., Montermini, L., Molto, M. D., Pianese, L., Cossee, M., Cavalcanti, F., Monros, E., Rodius, F., Duclos, F., Monticelli, A., Zara, F., Canizares, J., and 15 others. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 271: 1423-1427, 1996. 2. Carvajal, J. J., Pook, M. A., dos Santos, M., Doudney, K., Hillermann, R., Minogue, S., Williamson, R., Hsuan, J. J., Chamberlain, S. The Friedreich's ataxia gene encodes a novel phosphatidylinositol-4-phosphate 5-kinase. Nature Genet. 14: 157-162, 1996. 3. Carvajal, J. J., Pook, M. A., Doudney, K., Hillermann, R., Wilkes, D., Al-Mahdawi, S., Williamson, R., Chamberlain, S. Friedreich's ataxia: a defect in signal transduction? Hum. Molec. Genet. 4: 1411-1419, 1995.