Anti-PIP5K1A Antibody Picoband® HRP Conjugated

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Located in several cellular components, including lamellipodium; nucleus; and ruffle membrane.

PIP5K1A; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; PIP5K1-alpha; PtdIns (4P-5-kinase 1 alpha; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha

E.coli-derived human PIP5K1A recombinant protein (Position: I33-H562) . Human PIP5K1A shares 92.2% and 92.4% amino acid (aa) sequence identity with mouse and rat PIP5K1A, respectively.

1. Ishihara, H., Shibasaki, Y., Kizuki, N., Wada, T., Yazaki, Y., Asano, T., Oka, Y. Type I phosphatidylinositol-4-phosphate 5-kinases: cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. J. Biol. Chem. 273: 8741-8748, 1998. 2. Loijens, J. C., Anderson, R. A. Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family. J. Biol. Chem. 271: 32937-32943, 1996. 3. Mellman, D. L., Gonzales, M. L., Song, C., Barlow, C. A., Wang, P., Kendziorski, C., Anderson, R. A. A PtdIns4,5P (2) -regulated nuclear poly (A) polymerase controls expression of select mRNAs. Nature 451: 1013-1017, 2008.