Anti-RPL24 Antibody Picoband®

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

E.coli-derived human RPL24 recombinant protein (Position: M1-R157) . Human EIF3H shares 100% amino acid (aa) sequence identity with both mouse and rat RPL24.

1. Barkic, M., Crnomarkovic, S., Grabusic, K., Bogetic, I., Panic, L., Tamarut, S., Cokaric, M., Jeric, I., Vidak, S., Volarevic, S. The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Molec. Cell. Biol. 29: 2489-2504, 2009. 2. Barna, M., Pusic, A., Zollo, O., Costa, M., Kondrashov, N., Rego, E., Rao, P. H., Ruggero, D. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature 456: 971-975, 2008. 3. Johnson, K. R. Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30. Gene 123: 283-285, 1993.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.