Anti-REPS2 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
REPS2; POB1; RalBP1-associated Eps domain-containing protein 2; Partner of RalBP1; RalBP1-interacting protein 2
Gene Name
REPS2
Gene ID
9185
UniProt
Q8NFH8
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human REPS2 recombinant protein (Position: A76-K564) . Human REPS2 shares 88.4% amino acid (aa) sequence identity with mouse REPS2.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Feig, L. A. Ral-GTPases: approaching their 15 minutes of fame. Trends. Cell Biol. 13: 419-425, 2003. 2. Ikeda, M., Ishida, O., Hinoi, T., Kishida, S., Kikuchi, A. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J. Biol. Chem. 273: 814-821, 1998. 3. Kariya, K., Koyama, S., Nakashima, S., Oshiro, T., Morinaka, K., Kikuchi, A. Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation. J. Biol. Chem. 275: 18399-18406, 2000.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
72 kDa
Gene Name Synonym
RALBP1 associated Eps domain containing 2
Protein Name
RalBP1-associated Eps domain-containing protein 2
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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