Anti-CTRC Antibody Picoband® APC Conjugated

This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

A synthetic peptide corresponding to a sequence at the C-terminus of human CTRC, which shares 86.4% amino acid (aa) sequence identity with both mouse and rat CTRC.

1. Kang, J., Wiegand, U., Muller-Hill, B. Identification of cDNAs encoding two novel rat pancreatic serine proteases. Gene 110: 181-187, 1992. 2. Masson, E., Chen, J.-M., Scotet, V., Le Marechal, C., Ferec, C. Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis. Hum. Genet. 123: 83-91, 2008. 3. Rosendahl, J., Witt, H., Szmola, R., Bhatia, E., Ozsvari, B., Landt, O., Schulz, H.-U., Gress, T. M., Ptufzer, R., Lohr, M., Kovacs, P., Bluher, M., and 22 others. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nature Genet. 40: 78-82, 2008.