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Anti-CTRC Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Synonyms

CTRC; CLCR; Chymotrypsin-C; EC 3.4.21.2; Caldecrin

Gene Name

CTRC

Gene ID

11330

UniProt

Q99895

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CTRC, which shares 86.4% amino acid (aa) sequence identity with both mouse and rat CTRC.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Kang, J., Wiegand, U., Muller-Hill, B. Identification of cDNAs encoding two novel rat pancreatic serine proteases. Gene 110: 181-187, 1992. 2. Masson, E., Chen, J.-M., Scotet, V., Le Marechal, C., Ferec, C. Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis. Hum. Genet. 123: 83-91, 2008. 3. Rosendahl, J., Witt, H., Szmola, R., Bhatia, E., Ozsvari, B., Landt, O., Schulz, H.-U., Gress, T. M., Ptufzer, R., Lohr, M., Kovacs, P., Bluher, M., and 22 others. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nature Genet. 40: 78-82, 2008.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

29 kDa

Gene Name Synonym

Chymotrypsin C

Protein Name

Chymotrypsin-C

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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