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Anti-REM2 Antibody Picoband® APC Conjugated

Product Specifications

Background

Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity. Predicted to be active in plasma membrane.

Synonyms

REM2; GTP-binding protein REM 2; Rad and Gem-like GTP-binding protein 2

Gene Name

REM2

Gene ID

161253

UniProt

Q8IYK8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human REM2 recombinant protein (Position: R65-E257) . Human REM2 shares 94.8% and 95.9% amino acid (aa) sequence identity with mouse and rat REM2, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Bierings, R., Beato, M., Edel, M. J. An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19 (ARF) expression that promotes endothelial cell proliferation and angiogenesis. J. Biol. Chem. 283: 4408-4416, 2008. 2. Edel, M. J., Menchon, C., Menendez, S., Consiglio, A., Raya, A., Belmonte, J. C. I. Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. Genes Dev. 24: 561-573, 2010. 3. Finlin, B. S., Shao, H., Kadono-Okuda, K., Guo, N., Andres, D. A. Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases. Biochem. J. 347: 223-231, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

37 kDa

Applications Notes

6

Gene Name Synonym

RRAD and GEM like GTPase 2

Protein Name

GTP-binding protein REM 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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