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Anti-B7H6/NCR3LG1 Antibody Picoband® HRP Conjugated

Product Specifications

Background

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.

Synonyms

NCR3LG1; B7H6; Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; B7-H6

Gene Name

NCR3LG1

Gene ID

374383

UniProt

Q68D85

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human B7H6/NCR3LG1 recombinant protein (Position: H85-D386) .

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Brandt, C. S., Baratin, M., Yi, E. C., Kennedy, J., Gao, Z., Fox, B., Haldeman, B., Ostrander, C. D., Kaifu, T., Chabannon, C., Moretta, A., West, R., Xu, W., Vivier, E., Levin, S. D. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J. Exp. Med. 206: 1495-1503, 2009. 2. Li, Y., Wang, Q., Mariuzza, R. A. Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6. J. Exp. Med. 208: 703-714, 2011.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

51 kDa

Gene Name Synonym

Natural killer cell cytotoxicity receptor 3 ligand 1

Protein Name

Natural cytotoxicity triggering receptor 3 ligand 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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