Anti-B7H6/NCR3LG1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.
Synonyms
NCR3LG1; B7H6; Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; B7-H6
Gene Name
NCR3LG1
Gene ID
374383
UniProt
Q68D85
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human B7H6/NCR3LG1 recombinant protein (Position: H85-D386) .
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Brandt, C. S., Baratin, M., Yi, E. C., Kennedy, J., Gao, Z., Fox, B., Haldeman, B., Ostrander, C. D., Kaifu, T., Chabannon, C., Moretta, A., West, R., Xu, W., Vivier, E., Levin, S. D. The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans. J. Exp. Med. 206: 1495-1503, 2009. 2. Li, Y., Wang, Q., Mariuzza, R. A. Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6. J. Exp. Med. 208: 703-714, 2011.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
51 kDa
Gene Name Synonym
Natural killer cell cytotoxicity receptor 3 ligand 1
Protein Name
Natural cytotoxicity triggering receptor 3 ligand 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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