Anti-NARFL/CIAO3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Involved in several processes, including intracellular oxygen homeostasis; iron-sulfur cluster assembly; and response to hypoxia. Part of cytosolic [4Fe-4S] assembly targeting complex.
Synonyms
CIAO3; NARFL; PRN; Cytosolic iron-sulfur assembly component 3; Cytosolic Fe-S cluster assembly factor NARFL; Iron-only hydrogenase-like protein 1; IOP1; Nuclear prelamin A recognition factor-like protein; Protein related to Narf
Gene Name
CIAO3
Gene ID
64428
UniProt
Q9H6Q4
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NARFL/CIAO3 recombinant protein (Position: Y196-W476) . Human NARFL/CIAO3 shares 88.3% and 86.8% amino acid (aa) sequence identity with mouse and rat NARFL/CIAO3, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/19/2011. 2. Huang, J., Song, D., Flores, A., Zhao, Q., Mooney, S. M., Shaw, L. M., Lee, F. S. IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1-alpha activity. Biochem. J. 401: 341-352, 2007. 3. Song, D., Lee, F. S. Mouse knock-out of IOP1 protein reveals its essential role in mammalian cytosolic iron-sulfur protein biogenesis. J. Biol. Chem. 286: 15797-15805, 2011.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
53 kDa
Gene Name Synonym
Cytosolic iron-sulfur assembly component 3
Protein Name
Cytosolic iron-sulfur assembly component 3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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