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Anti-PYCRL/PYCR3 Antibody Picoband® HRP Conjugated

Product Specifications

Background

This gene encodes a protein that belongs to the pyrroline-5-carboxylate reductase family of enzymes. Members of this family catalyze the final step in proline biosynthesis, converting pyrroline-5-carboxylate to proline. Glutamate and ornithine are precursors in the synthesis of proline. The protein encoded by this gene is a cytoplasmic enzyme involved in the biosynthesis of proline from ornithine.

Synonyms

PYCR3; PYCRL; Pyrroline-5-carboxylate reductase 3; P5C reductase 3; P5CR 3; EC 1.5.1.2; Pyrroline-5-carboxylate reductase-like protein

Gene Name

PYCR3

Gene ID

65263

UniProt

Q53H96

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PYCRL/PYCR3 recombinant protein (Position: M1-D233) . Human PYCRL/PYCR3 shares 81.5% and 82.4% amino acid (aa) sequence identity with mouse and rat PYCRL/PYCR3, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. De Ingeniis, J., Ratnikov, B., Richardson, A. D., Scott, D. A., Aza-Blanc, P., De, S. K., Kazanov, M., Pellecchia, M., Ronai, Z., Osterman, A. L., Smith, J. W. Functional specialization in proline biosynthesis of melanoma. PLoS One 7: e45190, 2012. Note: Electronic Article.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

29 kDa

Gene Name Synonym

Pyrroline-5-carboxylate reductase 3

Protein Name

Pyrroline-5-carboxylate reductase 3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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