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Anti-NSUN7 Antibody Picoband® APC Conjugated

Product Specifications

Background

Predicted to enable RNA binding activity and methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to act upstream of or within flagellated sperm motility and sperm mitochondrion organization.

Synonyms

NSUN7; Putative methyltransferase NSUN7; EC 2.1.1.-; NOL1/NOP2/Sun domain family member 7

Gene Name

NSUN7

Gene ID

79730

UniProt

Q8NE18

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NSUN7 recombinant protein (Position: D83-Q457) . Human NSUN7 shares 79.2% amino acid (aa) sequence identity with mouse NSUN7.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Harris, T., Marquez, B., Suarez, S., Schimenti, J. Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases. Biol. Reprod. 77: 376-382, 2007. 2. Khosronezhad, N., Hosseinzadeh Colagar, A., Mortazavi, S. M. The Nsun7 (A11337) -deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. J. Assist. Reprod. Genet. 32: 807-815, 2015. 3. Ren, H. Y., Zhong, R., Ding, X. P., Chen, Z. Y., Jing, Y. L. Investigation of polymorphisms in exon7 of the NSUN7 gene among Chinese Han men with asthenospermia. Genet. Molec. Res. 14: 9261-9268, 2015.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

81 kDa

Applications Notes

6

Gene Name Synonym

NOP2/Sun RNA methyltransferase family member 7

Protein Name

Putative methyltransferase NSUN7

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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