Anti-NSUN6 Antibody Picoband® HRP Conjugated
Product Specifications
Background
Enables tRNA (cytidine-5-) -methyltransferase activity and tRNA binding activity. Involved in tRNA C5-cytosine methylation. Located in cytoplasm. Implicated in autosomal recessive intellectual developmental disorder 82.
Synonyms
NSUN6; NOPD1; tRNA; cytosine (72-C (5-methyltransferase NSUN6; EC 2.1.1.-; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family member 6
Gene Name
NSUN6
Gene ID
221078
UniProt
Q8TEA1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NSUN6 recombinant protein (Position: E40-E400) . Human NSUN6 shares 82.3% amino acid (aa) sequence identity with mouse NSUN6.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Chi, L., Delgado-Olguin, P. Expression of NOL1/NOP2/sun domain (Nsun) RNA methyltransferase family genes in early mouse embryogenesis. Gene Expr. Patterns 13: 319-327, 2013. 2. Gross, M. B. Personal Communication. Baltimore, Md. 11/10/2016. 3. Haag, S., Warda, A. S., Kretschmer, J., Gunnigmann, M. A., Hobartner, C., Bohnsack, M. T. NSUN6 is a human RNA methyltransferase that catalyzes formation of m (5) C72 in specific tRNAs. RNA 21: 1532-1543, 2015.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
52 kDa
Gene Name Synonym
NOP2/Sun RNA methyltransferase 6
Protein Name
TRNA (cytosine (72) -C (5) ) -methyltransferase NSUN6
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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