Anti-NEK11 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
Synonyms
NEK11; Serine/threonine-protein kinase Nek11; EC 2.7.11.1; Never in mitosis A-related kinase 11; NimA-related protein kinase 11
Gene Name
NEK11
Gene ID
79858
UniProt
Q8NG66
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NEK11 recombinant protein (Position: E72-Q630) . Human NEK11 shares 71.1% amino acid (aa) sequence identity with mouse NEK11.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. J. Biol. Chem. 277: 39655-39665, 2002. 2. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. J. Biol. Chem. 279: 32716-32727, 2004.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
74 kDa
Applications Notes
6
Gene Name Synonym
NIMA related kinase 11
Protein Name
Serine/threonine-protein kinase Nek11
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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