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Anti-NEK11 Antibody Picoband® Fluoro594 Conjugated

Selected Variant

A10929-2-Fluoro594

Size: 100 µg/Vial

Product Specifications

Background

This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.

Synonyms

NEK11; Serine/threonine-protein kinase Nek11; EC 2.7.11.1; Never in mitosis A-related kinase 11; NimA-related protein kinase 11

Gene Name

NEK11

Gene ID

79858

UniProt

Q8NG66

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NEK11 recombinant protein (Position: E72-Q630) . Human NEK11 shares 71.1% amino acid (aa) sequence identity with mouse NEK11.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. J. Biol. Chem. 277: 39655-39665, 2002. 2. Noguchi, K., Fukazawa, H., Murakami, Y., Uehara, Y. Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells. J. Biol. Chem. 279: 32716-32727, 2004.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

74 kDa

Applications Notes

6

Gene Name Synonym

NIMA related kinase 11

Protein Name

Serine/threonine-protein kinase Nek11

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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