Anti-Chromogranin A/CGA Antibody Picoband®

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene.

CGA; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain

A synthetic peptide corresponding to a sequence at the N-terminus of human Chromogranin A/CGA, which shares 78.3% amino acid (aa) sequence identity with mouse Chromogranin A/CGA.

1. Boothby, M., Ruddon, R. W., Anderson, C., McWilliams, D., Boime, I. A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines. J. Biol. Chem. 256: 5121-5127, 1981. 2. Bordelon, M., Kohler, P. O. Synthesis of human glycoprotein hormone in somatic cell hybrids. (Abstract) J. Cell Biol. 67: 37A only, 1975. 3. Bordelon-Riser, M. E., Siciliano, M. J., Kohler, P. O. Necessity for two human chromosomes for human chorionic gonadotropin production in human-mouse hybrids. Somat. Cell Genet. 5: 597-613, 1979.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.