Anti-MYL6 Antibody Picoband® Fluoro647 Conjugated

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.

MYL6; Myosin light polypeptide 6; 17 kDa myosin light chain; LC17; Myosin light chain 3; MLC-3; Myosin light chain alkali 3; Myosin light chain A3; Smooth muscle and nonmuscle myosin light chain alkali 6

1. Bora, P. S., Bora, N. S., Wu, X., Kaplan, H. J., Lange, L. G. Molecular cloning, sequencing, and characterization of smooth muscle myosin alkali light chain from human eye cDNA: homology with myocardial fatty acid ethyl ester synthase-III cDNA. Genomics 19: 186-188, 1994. 2. Hailstones, D. L., Gunning, P. W. Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function. Molec. Cell. Biol. 10: 1095-1104, 1990. 3. Lenz, S., Lohse, P., Seidel, U., Arnold, H.-H. The alkali light chains of human smooth and nonmuscle myosins are encoded by a single gene: tissue-specific expression by alternative splicing pathways. J. Biol. Chem. 264: 9009-9015, 1989.