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Anti-BRD1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants.

Synonyms

BRD1; BRL; BRPF2; Bromodomain-containing protein 1; BR140-like protein; Bromodomain and PHD finger-containing protein 2

Gene Name

BRD1

Gene ID

23774

UniProt

O95696

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human BRD1 recombinant protein (Position: R395-Q913) . Human BRD1 shares 92.9% amino acid (aa) sequence identity with mouse BRD1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. McCullagh, P., Chaplin, T., Meerabux, J., Grenzelias, D., Lillington, D., Poulsom, R., Gregorini, A., Saha, V., Young, B. D. The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene. Oncogene 18: 7442-7452, 1999.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

120 kDa

Applications Notes

6

Gene Name Synonym

Bromodomain containing 1

Protein Name

Bromodomain-containing protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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