Anti-ADH6 Antibody Picoband®

Alcohol dehydrogenase 6 is an enzyme that in humans is encoded by the ADH6 gene. This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

1. Osier, M. V., Pakstis, A. J., Soodyall, H., Comas, D., Goldman, D., Odunsi, A., Okonofua, F., Parnas, J., Schulz, L. O., Bertranpetit, J., Bonne-Tamir, B., Lu, R.-B., Kidd, J. R., Kidd, K. K. A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am. J. Hum. Genet. 71: 84-99, 2002. 2. Yasunami, M., Chen, C.-S., Yoshida, A. A human alcohol dehydrogenase gene (ADH6) encoding an additional class of isozyme. Proc. Nat. Acad. Sci. 88: 7610-7614, 1991.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.