Anti-ARL2 Antibody Picoband® Fluoro488 Conjugated

ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene. This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF) . The encoded protein is one of a functionally distinct group of ARF-like genes.

A synthetic peptide corresponding to a sequence at the C-terminus of human ARL2, which shares 90.9% amino acid (aa) sequence identity with mouse and rat ARL2.

1. Bowzard, J. B., Cheng, D., Peng, J., Kahn, R. A. ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs. J. Biol. Chem. 282: 17568-17580, 2007. 2. Cai, X.-B., Wu, K.-C., Zhang, X., Lv, J.-N., Jin, G.-H., Xiang, L., Chen, J., Huang, X.-F., Pan, D., Lu, B., Lu, F., Qu, J., Jin, Z.-B. Whole-exome sequencing identified ARL2 as a novel candidate gene for MRCS (microcornea, rod-cone dystrophy, cataract, and posterior staphyloma) syndrome. Clin. Genet. 96: 61-71, 2019. 3. Clark, J., Moore, L., Krasinskas, A., Way, J., Battey, J., Tamkun, J., Kahn, R. A. Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes. Proc. Nat. Acad. Sci. 90: 8952-8956, 1993.