Anti-OAT1/SLC22A6 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.
Gene Name
SLC22A6
Gene ID
9356
UniProt
Q4U2R8
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human OAT1/SLC22A6 recombinant protein (Position: R286-L563) . Human SLC22A6 shares 82% and 83.8% amino acid (aa) sequence identity with mouse and rat SLC22A6, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Bahn, A., Prawitt, D., Buttler, D., Reid, G., Enklaar, T., Wolff, N. A., Ebbinghaus, C., Hillemann, A., Schulten, H.-J., Gunawan, B., Fuzesi, L., Zabel, B., Burckhardt, G. Genomic structure and in vivo expression of the human organic anion transporter 1 (hOAT1) gene. Biochem. Biophys. Res. Commun. 275: 623-630, 2000. 2. Lu, R., Chan, B. S., Schuster, V. L. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. Am. J. Physiol. 276: F295-F303, 1999. 3. Race, J. E., Grassl, S. M., Williams, W. J., Holtzman, E. J. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3) . Biochem. Biophys. Res. Commun. 255: 508-514, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
62 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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