Anti-LZTS2 Antibody Picoband® Fluoro488 Conjugated

The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

E.coli-derived human LZTS2 recombinant protein (Position: M1-I669) . Human LZTS2 shares 91.7% and 90.5% amino acid (aa) sequence identity with mouse and rat LZTS2, respectively.

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