Anti-NCLN Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Nicalin is a protein that in humans is encoded by the NCLN gene. Enables ribosome binding activity. Involved in protein stabilization; regulation of protein complex stability; and regulation of protein-containing complex assembly. Located in endoplasmic reticulum membrane. Part of protein-containing complex.
Gene Name
NCLN
Gene ID
56926
UniProt
Q969V3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human NCLN recombinant protein (Position: Q59-Q563) . Human NCLN shares 92.9% and 92.5% amino acid (aa) sequence identity with mouse and rat NCLN, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Dettmer, U., Kuhn, P.-H., Abou-Ajram, C., Lichtenthaler, S. F., Kruger, M., Kremmer, E., Haass, C., Haffner, C. Transmembrane protein 147 (TMEM147) is a novel component of the nicalin-NOMO protein complex. J. Biol. Chem. 285: 26174-26181, 2010. 2. Haffner, C., Frauli, M., Topp, S., Irmler, M., Hofmann, K., Regula, J. T., Bally-Cuif, L., Haass, C. Nicalin and its binding partner Nomo are novel Nodal signaling antagonists. EMBO J. 23: 3041-3050, 2004. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 08/17/2021.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
63 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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