Anti-METT5D1/METTL15 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Predicted to enable rRNA (cytosine-N4-) -methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane.
Gene Name
METTL15
Gene ID
196074
UniProt
P0C7V9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human METT5D1/METTL15 recombinant protein (Position: R200-L407) . Human METTL15 shares 87% amino acid (aa) sequence identity with mouse METTL15.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Chen, H., Shi, Z., Guo, J., Chang, K. J., Chen, Q., Yao, C. H., Haigis, M. C., Shi, Y. The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function. J. Biol. Chem. 295: 8505-8513, 2020. 2. Gross, M. B. Personal Communication. Baltimore, Md. 12/19/2019. 3. Itoh, Y., Khawaja, A., Laptev, I., Cipullo, M., Atanassov, I., Sergiev, P., Rorbach, J., Amunts, A. Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606: 603-608, 2022.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
46 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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