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Anti-METT5D1/METTL15 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Predicted to enable rRNA (cytosine-N4-) -methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane.

Gene Name

METTL15

Gene ID

196074

UniProt

P0C7V9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human METT5D1/METTL15 recombinant protein (Position: R200-L407) . Human METTL15 shares 87% amino acid (aa) sequence identity with mouse METTL15.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Chen, H., Shi, Z., Guo, J., Chang, K. J., Chen, Q., Yao, C. H., Haigis, M. C., Shi, Y. The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function. J. Biol. Chem. 295: 8505-8513, 2020. 2. Gross, M. B. Personal Communication. Baltimore, Md. 12/19/2019. 3. Itoh, Y., Khawaja, A., Laptev, I., Cipullo, M., Atanassov, I., Sergiev, P., Rorbach, J., Amunts, A. Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606: 603-608, 2022.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

46 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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