Anti-METT5D1/METTL15 Antibody Picoband®

Predicted to enable rRNA (cytosine-N4-) -methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane.

E.coli-derived human METT5D1/METTL15 recombinant protein (Position: R200-L407) . Human METTL15 shares 87% amino acid (aa) sequence identity with mouse METTL15.

1. Chen, H., Shi, Z., Guo, J., Chang, K. J., Chen, Q., Yao, C. H., Haigis, M. C., Shi, Y. The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for mitochondrial function. J. Biol. Chem. 295: 8505-8513, 2020. 2. Gross, M. B. Personal Communication. Baltimore, Md. 12/19/2019. 3. Itoh, Y., Khawaja, A., Laptev, I., Cipullo, M., Atanassov, I., Sergiev, P., Rorbach, J., Amunts, A. Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature 606: 603-608, 2022.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.