Anti-Nir2/PITPNM1 Antibody Picoband®

Membrane-associated phosphatidylinositol transfer protein 1 is a protein that in humans is encoded by the PITPNM1 gene. PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein.

E.coli-derived human Nir2/PITPNM1 recombinant protein (Position: E418-R831) . Human PITPNM1 shares 88.9% and 89.9% amino acid (aa) sequence identity with mouse and rat PITPNM1, respectively.

1. Chang, J. T., Milligan, S., Li, Y., Chew, C. E., Wiggs, J., Copeland, N. G., Jenkins, N. A., Campochiaro, P. A., Hyde, D. R., Zack, D. J. Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype. J. Neurosci. 17: 5881-5890, 1997. 2. Lev, S., Hernandez, J., Martinez, R., Chen, A., Plowman, G., Schlessinger, J. Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. Molec. Cell. Biol. 19: 2278-2288, 1999. 3. Litvak, V., Tian, D., Carmon, S., Lev, S. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis. Molec. Cell. Biol. 22: 5064-5075, 2002.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.