Anti-RASL12 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Belonging to the small GTPase superfamily/Ras family, RASL12 is localized in the cellular membrane and cytoplasm. RASL12 has many important molecular functions including GTP binding, GTPase activity and nucleotide binding. The main biological function of this gene is to participate in the GTP catabolic process, signal transduction and small GTPase mediated signal transduction. RASL12 interacts with ACVR1, SMAD1, SMAD2, SMAD3 and SMURF2. Documented diseases associated with RASL12 include acute kidney tubular necrosis, intraepithelial neoplasm, retinitis, endometrial cancer, coronary artery disease and Huntington's disease.
Gene Name
RASL12
Gene ID
51285
UniProt
Q9NYN1
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human RASL12 recombinant protein (Position: K7-K261) . Human RASL12 shares 93.3% amino acid (aa) sequence identity with mouse RASL12.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Wistow, G., Bernstein, S. L., Ray, S., Wyatt, M. K., Behal, A., Touchman, J. W., ... & Peterson, K. (2002) . Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. Mol Vis, 8 (21), 185-195. 2. Barrios-Rodiles, M., Brown, K. R., Ozdamar, B., Bose, R., Liu, Z., Donovan, R. S., ... & Wrana, J. L. (2005) . High-throughput mapping of a dynamic signaling network in mammalian cells. Science, 307 (5715), 1621-1625. 3. Lipp, J. J., Marvin, M. C., Shokat, K. M., & Guthrie, C. (2015) . SR protein kinases promote splicing of nonconsensus introns. Nature structural & molecular biology, 22 (8), 611.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
30,29,27 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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