Anti-Ceacam1 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1) is thought to be a member of the immunoglobulin superfamily and is known as an epithelial tumor suppressor and an angiogenic growth factor. It has also been linked to the actin-based cytoskeleton. CEACAM1 is also known as a cellular receptor for a number of human mucosa pathogenic bacteria. The loss of activity of CEACAM1 has been related to the development of colorectal cancer.
Gene Name
Ceacam1
Gene ID
26365
UniProt
P31809
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
E.coli-derived mouse Ceacam1 recombinant protein (Position: A34-D382) . Mouse Ceacam1 shares 55.5% and 68.8% amino acid (aa) sequence identity with human and rat Ceacam1, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Abou-Rjaily, G. A., Lee, S. J., May, D., Al-Share, Q. Y., DeAngelis, A. M., Ruch, R. J., Neumaier, M., Kalthoff, H., Lin, S.-H., Najjar, S. M. CEACAM1 modulates epidermal growth factor receptor-mediated cell proliferation. J. Clin. Invest. 114: 944-952, 2004. 2. Barnett, T., Zimmermann, W. Workshop report: proposed nomenclature for the carcinoembryonic antigen (CEA) gene family. Tumour Biol. 11: 59-63, 1990. 3. Beauchemin, N., Draber, P., Dveksler, G., Gold, P., Gray-Owen, S., Grunert, F., Hammarstrom, S., Holmes, K. V., Karlsson, A., Kuroki, M., Lin, S.-H., Lucka, L., and 13 others. Redefined nomenclature for members of the carcinoembryonic antigen family. Exp. Cell Res. 252: 243-249, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
57,50,37,30 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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