Anti-Lamin B2/LMNB2 Antibody Picoband® Fluoro488 Conjugated

Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

E.coli-derived human Lamin B2/LMNB2 recombinant protein (Position: L128-E585) . Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.

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