Anti-PLD5 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Phospholipase D family, member 5 is a protein that in humans is encoded by the PLD5 gene. Inactive phospholipase D5 (PLD5) is a variant of the phospholipase D enzyme family that lacks catalytic activity due to mutations or alterations in critical amino acid residues. Despite its inactivity, PLD5 is believed to contribute to cellular processes such as lipid metabolism and membrane dynamics, highlighting its potential regulatory roles in cellular signaling pathways.
Gene Name
PLD5
Gene ID
200150
UniProt
Q8N7P1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human PLD5 recombinant protein (Position: K247-K517) . Human PLD5 shares 95.9% amino acid (aa) sequence identity with mouse PLD5.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Liu, J., Li, J., Ma, Y., Xu, C., Wang, Y., & He, Y. (2021) . MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer. Bioengineered, 12 (1), 3240-3251. 2. Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., ... & Gill, M. (2010) . A genome-wide scan for common alleles affecting risk for autism. Human molecular genetics, 19 (20), 4072-4082. 3. McCauley, J. L., Zuvich, R. L., Bradford, Y., Kenealy, S. J., Schnetz-Boutaud, N., Gregory, S. G., ... & Haines, J. L. (2009) . Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes & Immunity, 10 (7), 624-630.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
61,51,38,54 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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