Anti-PLD5 Antibody Picoband®

Phospholipase D family, member 5 is a protein that in humans is encoded by the PLD5 gene. Inactive phospholipase D5 (PLD5) is a variant of the phospholipase D enzyme family that lacks catalytic activity due to mutations or alterations in critical amino acid residues. Despite its inactivity, PLD5 is believed to contribute to cellular processes such as lipid metabolism and membrane dynamics, highlighting its potential regulatory roles in cellular signaling pathways.

1. Liu, J., Li, J., Ma, Y., Xu, C., Wang, Y., & He, Y. (2021) . MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer. Bioengineered, 12 (1), 3240-3251. 2. Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T. R., ... & Gill, M. (2010) . A genome-wide scan for common alleles affecting risk for autism. Human molecular genetics, 19 (20), 4072-4082. 3. McCauley, J. L., Zuvich, R. L., Bradford, Y., Kenealy, S. J., Schnetz-Boutaud, N., Gregory, S. G., ... & Haines, J. L. (2009) . Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes & Immunity, 10 (7), 624-630.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.