Anti-SYNJ2BP Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Synaptojanin-2-binding protein is a protein that in humans is encoded by the SYNJ2BP gene. SYNJ2BP, also known as Synaptojanin 2 Binding Protein, is a protein that interacts with synaptojanin 2, a phosphoinositide phosphatase found in synaptic vesicles. Synaptojanin 2 plays a crucial role in neurotransmitter release and synaptic transmission in neurons, and SYNJ2BP is implicated in regulating these processes through its interaction with synaptojanin 2. The precise molecular and cellular mechanisms of SYNJ2BP are still under investigation, with research focusing on its involvement in neural development, functional abnormalities, and neurologic disorders.
Gene Name
SYNJ2BP
Gene ID
55333
UniProt
P57105
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human SYNJ2BP recombinant protein (Position: D32-L145) . Human SYNJ2BP shares 88.6% and 86.8% amino acid (aa) sequence identity with mouse and rat SYNJ2BP, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Matsuzaki, T., Hanai, S., Kishi, H., Liu, Z., Bao, Y., Kikuchi, A., Tsuchida, K., Sugino, H. Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway. J. Biol. Chem. 277: 19008-19018, 2002. 2. Nemoto, Y., De Camilli, P. Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. EMBO J. 18: 2991-3006, 1999. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 01/18/2022.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
16 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items