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Anti-SYNJ2BP Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Synaptojanin-2-binding protein is a protein that in humans is encoded by the SYNJ2BP gene. SYNJ2BP, also known as Synaptojanin 2 Binding Protein, is a protein that interacts with synaptojanin 2, a phosphoinositide phosphatase found in synaptic vesicles. Synaptojanin 2 plays a crucial role in neurotransmitter release and synaptic transmission in neurons, and SYNJ2BP is implicated in regulating these processes through its interaction with synaptojanin 2. The precise molecular and cellular mechanisms of SYNJ2BP are still under investigation, with research focusing on its involvement in neural development, functional abnormalities, and neurologic disorders.

Gene Name

SYNJ2BP

Gene ID

55333

UniProt

P57105

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human SYNJ2BP recombinant protein (Position: D32-L145) . Human SYNJ2BP shares 88.6% and 86.8% amino acid (aa) sequence identity with mouse and rat SYNJ2BP, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Matsuzaki, T., Hanai, S., Kishi, H., Liu, Z., Bao, Y., Kikuchi, A., Tsuchida, K., Sugino, H. Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway. J. Biol. Chem. 277: 19008-19018, 2002. 2. Nemoto, Y., De Camilli, P. Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein. EMBO J. 18: 2991-3006, 1999. 3. Stumpf, A. M. Personal Communication. Baltimore, Md. 01/18/2022.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

16 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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