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Anti-RTL1 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

RTL1 (retrotransposon like 1) is a retrotransposon derived protein coding gene. This gene is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. This gene is essential for maintenance of the fetal capillaries.

Gene Name

RTL1

Gene ID

388015

UniProt

A6NKG5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human RTL1 recombinant protein (Position: H446-R1327) . Human RTL1 shares 68.3% amino acid (aa) sequence identity with mouse RTL1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Davis, E., Caiment, F., Tordoir, X., Cavailli, J., Ferguson-Smith, A., Cockett, N., Georges, M., Charlier, C. RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus. Curr. Biol. 15: 743-749, 2005. Note: Erratum: Curr. Biol. 15: 884 only, 2005. 2. Kagami, M., Sekita, Y., Nishimura, G., Irie, M., Kato, F., Okada, M., Yamamori, S., Kishimoto, H., Nakayama, M., Tanaka, Y., Matsuoka, K., Takahashi, T., and 12 others. Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd (14) -like phenotypes. Nature Genet. 40: 237-242, 2008. 3. Seitz, H., Youngson, N., Lin, S.-P., Dalbert, S., Paulsen, M., Bachellerie, J.-P., Ferguson-Smith, A. C., Cavaille, J. Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nature Genet. 34: 261-262, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

155 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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