Anti-GLMN Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Glomulin is a protein that in humans is encoded by the GLMN gene. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Multiple splice variants encoding different isoforms have been found for this gene.
Gene Name
GLMN
Gene ID
11146
UniProt
Q92990
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human GLMN recombinant protein (Position: Q153-R574) . Human GLMN shares 85.4% amino acid (aa) sequence identity with mouse GLMN.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Arai, T., Kasper, J. S., Skaar, J. R., Ali, S. H., Takahashi, C., DeCaprio, J. A. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Nat. Acad. Sci. 100: 9855-9860, 2003. 2. Brouillard, P., Boon, L. M., Mulliken, J. B., Enjolras, O., Ghassibe, M., Warman, M. L., Tan, O. T., Olsen, B. R., Vikkula, M. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ('glomangiomas') . Am. J. Hum. Genet. 70: 866-874, 2002. 3. Brouillard, P., Olsen, B. R., Vikkula, M. High-resolution physical and transcript map of the locus for venous malformations with glomus cells (VMGLOM) on chromosome 1p21-p22. Genomics 67: 96-101, 2000.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
68 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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